Basic Information
ID: ALA5134965
Type: Binding
Description: Inhibition of FLT3 ITD mutant in human MV4-11 cells assessed as reduction in STAT3 phosphorylation at Y694 residue at 5 to 25 nM measured after 1 hr by immunoblotting analysis
Organism: Homo sapiens
Cell type: MV4-11
Activity Charts
Bioactivity
Activity Types for Assay ALA5134965
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 405.55 | 4.24 | 4.24 |
| 560.68 | 5.86 | 5.86 |
| 391.52 | 4.37 | 4.37 |
| 534.76 | 4.50 | 4.50 |
| 505.67 | 3.84 | 3.84 |
| 591.85 | 4.48 | 4.48 |
| 434.55 | 3.47 | 3.47 |
| 562.77 | 3.82 | 3.82 |
| 477.66 | 4.52 | 4.52 |
| 576.79 | 3.68 | 3.68 |
| 519.70 | 3.70 | 3.70 |