Basic Information
ID: ALA5135014
Type: Binding
Description: Antagonist activity at PAC-1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of PACAP-induced CREB phosphorylation at 1 nM pretreated for 30 mins followed by PACAP stimulation for 30 mins by western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Pituitary adenylate cyclase-activating polypeptide type I receptor(ALA5399)
Document: ALA5131488
Antagonist activity at PAC-1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of PACAP-induced CREB phosphorylation at 1 nM pretreated for 30 mins followed by PACAP stimulation for 30 mins by western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5135014
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.34 | 1.23 | 1.23 |
| 314.35 | 1.61 | 1.61 |
| 286.29 | 0.83 | 0.83 |
| 312.33 | 1.39 | 1.39 |
| 344.37 | 1.62 | 1.62 |
| 330.34 | 1.23 | 1.23 |
| 379.21 | 1.99 | 1.99 |
| 314.35 | 1.53 | 1.53 |
| 298.35 | 1.78 | 1.78 |
| 312.37 | 2.17 | 2.17 |
| 335.16 | 1.59 | 1.59 |
| 334.76 | 1.88 | 1.88 |
| 284.32 | 1.39 | 1.39 |
| 340.26 | 1.72 | 1.72 |
| 344.37 | 1.62 | 1.62 |
| 344.37 | 1.62 | 1.62 |
| 292.25 | 1.10 | 1.10 |
| 290.71 | 1.48 | 1.48 |
| 300.32 | 1.22 | 1.22 |
| 342.36 | 1.40 | 1.40 |