Basic Information
ID: ALA5135018
Type: Binding
Description: Antagonist activity at PAC-1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of PACAP-induced increase in intracellular cAMP level pretreated for 30 mins followed by PACAP stimulation measured after 1 hr by cAMP-Glo assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Pituitary adenylate cyclase-activating polypeptide type I receptor(ALA5399)
Document: ALA5131488
Antagonist activity at PAC-1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of PACAP-induced increase in intracellular cAMP level pretreated for 30 mins followed by PACAP stimulation measured after 1 hr by cAMP-Glo assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5135018
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.26 | 1.72 | 1.72 |
| 342.36 | 1.40 | 1.40 |