Metabolic stability in human liver microsomes assessed as parent compound remaining in presence of NADPH at 0.5 uM measured after 10 mins by LC-MS/MS ...

Basic Information

ID: ALA5135027

Type: ADME

Description: Metabolic stability in human liver microsomes assessed as parent compound remaining in presence of NADPH at 0.5 uM measured after 10 mins by LC-MS/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target: ADMET(ALA612558)

Document: ALA5131488

Metabolic stability in human liver microsomes assessed as parent compound remaining in presence of NADPH at 0.5 uM measured after 10 mins by LC-MS/MS analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA5135027

Stability

Total(3)

Parent Molecular Weight	ALogP	Polar Surface Area
340.26	1.72	1.72
300.32	1.22	1.22
342.36	1.40	1.40

Parent Molecular Weight

ALogP

Polar Surface Area

340.26

1.72

300.32

1.22

342.36

1.40

Metabolic stability in human liver microsomes assessed as parent compound remaining in presence of NADPH at 0.5 uM measured after 10 mins by LC-MS/MS ...

Basic Information

Activity Charts

Compound Summary