Basic Information
ID: ALA5135074
Type: Toxicity
Description: Selectivity index, ratio of CC50 for human MRC-5 cells to EC50 for antitrypanosomal activity against intracellular Trypanosoma cruzi Tulahuen amastigotes expressing CL2 beta-galactosidase in human MRC5 cells
Format: BAO_0000219
Target: ADMET(ALA612558)
Document: ALA5131491
Selectivity index, ratio of CC50 for human MRC-5 cells to EC50 for antitrypanosomal activity against intracellular Trypanosoma cruzi Tulahuen amastigotes expressing CL2 beta-galactosidase in human MRC5 cells: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5135074
Selectivity Index
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.26 | -1.38 | -1.38 |
| 342.36 | 0.79 | 0.79 |
| 334.38 | 0.03 | 0.03 |
| 280.28 | -0.92 | -0.92 |
| 294.31 | -0.89 | -0.89 |
| 265.27 | -0.77 | -0.77 |
| 266.26 | -1.38 | -1.38 |
| 308.34 | -0.14 | -0.14 |
| 348.40 | 0.28 | 0.28 |
| 281.27 | -1.79 | -1.79 |
| 264.29 | 0.11 | 0.11 |
| 356.38 | 0.65 | 0.65 |
| 280.28 | -0.92 | -0.92 |
| 294.31 | -0.53 | -0.53 |
| 306.32 | -0.75 | -0.75 |
| 322.37 | 0.25 | 0.25 |
| 306.32 | -0.38 | -0.38 |
| 334.38 | 0.40 | 0.40 |
| 306.32 | -0.36 | -0.36 |
| 348.40 | 0.79 | 0.79 |
| 265.27 | -0.77 | -0.77 |