Selectivity index, ratio of CC50 for Swiss mouse peritoneal macrophages to EC50 for antileishmanial activity against intracellular Leishmania infantum...

Basic Information

ID: ALA5135077

Type: Toxicity

Description: Selectivity index, ratio of CC50 for Swiss mouse peritoneal macrophages to EC50 for antileishmanial activity against intracellular Leishmania infantum MHOM/MA(BE)/67 amastigotes infected in Swiss mouse peritoneal macrophages

Format: BAO_0000219

Target: ADMET(ALA612558)

Document: ALA5131491

Selectivity index, ratio of CC50 for Swiss mouse peritoneal macrophages to EC50 for antileishmanial activity against intracellular Leishmania infantum MHOM/MA(BE)/67 amastigotes infected in Swiss mouse peritoneal macrophages: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA5135077

Selectivity Index

Total(14)

Parent Molecular Weight	ALogP	Polar Surface Area
266.26	-1.38	-1.38
342.36	0.79	0.79
334.38	0.03	0.03
280.28	-0.92	-0.92
265.27	-0.77	-0.77
348.40	0.28	0.28
281.27	-1.79	-1.79
356.38	0.65	0.65
294.31	-0.53	-0.53
322.37	0.25	0.25
306.32	-0.38	-0.38
334.38	0.40	0.40
306.32	-0.36	-0.36
348.40	0.79	0.79

Parent Molecular Weight

ALogP

Polar Surface Area

266.26

-1.38

342.36

0.79

334.38

0.03

280.28

-0.92

265.27

-0.77

348.40

0.28

281.27

-1.79

356.38

0.65

294.31

-0.53

322.37

0.25

306.32

-0.38