Basic Information
ID: ALA5135713
Type: Binding
Description: Inhibition of FGFR2 K310R/N549K mutant in human AN3-CA cells assessed as inhibition of FGFalpha-stimulated PLCgamma phosphorylation at Tyr783 residue pretreated for 2 hrs followed by incubation with FGFalpha/heparin sulfate for 20 mins by western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: AN3-CA
Target: Unchecked(ALA612545)
Document: ALA5131515
Inhibition of FGFR2 K310R/N549K mutant in human AN3-CA cells assessed as inhibition of FGFalpha-stimulated PLCgamma phosphorylation at Tyr783 residue pretreated for 2 hrs followed by incubation with FGFalpha/heparin sulfate for 20 mins by western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5135713
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 581.51 | 5.89 | 5.89 |
| 542.43 | 4.87 | 4.87 |
| 584.51 | 5.99 | 5.99 |