Basic Information
ID: ALA5135714
Type: Binding
Description: Inhibition of TEL-V555M-FGFR3 mutant (unknown origin) transformed in serum starved mouse BaF3 cells assessed as inhibition of FGFalpha-stimulated FGFR3 phosphorylation at Tyr653/654 residues at 1 to 5 uM pretreated for 2 hrs followed by incubation with FGFalpha/heparin sulfate for 20 mins by western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: BaF3
Target: Unchecked(ALA612545)
Document: ALA5131515
Inhibition of TEL-V555M-FGFR3 mutant (unknown origin) transformed in serum starved mouse BaF3 cells assessed as inhibition of FGFalpha-stimulated FGFR3 phosphorylation at Tyr653/654 residues at 1 to 5 uM pretreated for 2 hrs followed by incubation with FGFalpha/heparin sulfate for 20 mins by western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5135714
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 581.51 | 5.89 | 5.89 |
| 542.43 | 4.87 | 4.87 |
| 584.51 | 5.99 | 5.99 |