Basic Information
ID: ALA5135795
Type: Functional
Description: In vivo inhibition of FGFR in BALB/c mouse xenografted with mouse BaF3 cells harboring TEL-V555M-FGFR3 mutant assessed as decrease in pFGFR levels in tumor tissue at 30 mg/kg, po qd for 15 days and measured at 4 hrs post-last dosage by immunohistochemistry analysis
Organism: Mus musculus
Strain: BALB/c
Cell type: BaF3
Activity Charts
Bioactivity
Activity Types for Assay ALA5135795
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 542.43 | 4.87 | 4.87 |