Basic Information
ID: ALA5135801
Type: Functional
Description: In vivo inhibition of FGFR in BALB/c mouse xenografted with human AN3-CA cells assessed as decrease in pFGFR levels in tumor tissue at 20 to 40 mg/kg, po qd for 15 days and measured at 4 hrs after last dosage by immunohistochemistry analysis
Organism: Mus musculus
Strain: BALB/c
Activity Charts
Bioactivity
Activity Types for Assay ALA5135801
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 542.43 | 4.87 | 4.87 |