Basic Information
ID: ALA5135840
Type: Functional
Description: Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct dye based FLIPR Tetra assay
Organism: Homo sapiens
Cell type: Flp-In-T-REx-293
Activity Charts
Bioactivity
Activity Types for Assay ALA5135840
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 212.68 | 1.37 | 1.37 |
| 335.23 | 3.76 | 3.76 |
| 333.26 | 4.36 | 4.36 |
| 335.23 | 3.76 | 3.76 |
| 369.30 | 5.21 | 5.21 |
| 325.28 | 4.59 | 4.59 |
| 333.26 | 4.25 | 4.25 |
| 353.68 | 4.71 | 4.71 |
| 335.23 | 3.76 | 3.76 |
| 282.77 | 4.06 | 4.06 |
| 296.80 | 4.36 | 4.36 |
| 300.79 | 3.11 | 3.11 |
| 375.32 | 5.27 | 5.27 |
| 318.78 | 3.25 | 3.25 |
| 328.80 | 3.77 | 3.77 |
| 252.75 | 2.47 | 2.47 |
| 359.71 | 4.77 | 4.77 |
| 320.77 | 3.68 | 3.68 |
| 316.79 | 2.81 | 2.81 |
| 330.83 | 4.13 | 4.13 |
| 318.78 | 3.25 | 3.25 |
| 254.74 | 2.90 | 2.90 |
| 397.68 | 4.01 | 4.01 |
| 398.13 | 4.82 | 4.82 |
| 332.81 | 3.56 | 3.56 |
| 282.32 | 3.25 | 3.25 |
| 268.76 | 3.29 | 3.29 |
| 285.22 | 3.81 | 3.81 |
| 395.68 | 3.58 | 3.58 |
| 399.32 | 5.22 | 5.22 |
| 390.87 | 3.13 | 3.13 |
| 304.78 | 1.84 | 1.84 |
| 347.29 | 4.67 | 4.67 |
| 318.78 | 3.25 | 3.25 |
| 308.83 | 4.07 | 4.07 |
| 266.32 | 3.54 | 3.54 |
| 308.81 | 3.60 | 3.60 |
| 314.82 | 3.42 | 3.42 |
| 392.86 | 3.57 | 3.57 |
| 327.26 | 3.43 | 3.43 |
| 271.19 | 3.42 | 3.42 |
| 332.81 | 3.55 | 3.55 |
| 306.84 | 3.64 | 3.64 |
| 368.79 | 4.13 | 4.13 |
| 338.24 | 3.66 | 3.66 |
| 362.83 | 3.56 | 3.56 |
| 358.87 | 4.76 | 4.76 |
| 351.23 | 3.47 | 3.47 |
| 381.68 | 4.30 | 4.30 |
| 369.68 | 4.42 | 4.42 |
| 397.68 | 4.01 | 4.01 |
| 330.83 | 4.16 | 4.16 |
| 288.80 | 4.12 | 4.12 |
| 409.36 | 5.84 | 5.84 |
| 316.79 | 2.81 | 2.81 |
| 404.16 | 4.88 | 4.88 |
| 321.76 | 3.08 | 3.08 |
| 321.78 | 3.15 | 3.15 |
| 316.79 | 2.81 | 2.81 |
| 395.68 | 3.58 | 3.58 |
| 397.68 | 4.01 | 4.01 |
| 337.23 | 4.20 | 4.20 |
| 349.26 | 4.07 | 4.07 |
| 309.80 | 3.00 | 3.00 |
| 321.21 | 2.85 | 2.85 |
| 362.83 | 3.56 | 3.56 |
| 328.84 | 3.69 | 3.69 |
| 306.82 | 3.17 | 3.17 |
| 414.13 | 4.52 | 4.52 |
| 338.21 | 3.59 | 3.59 |
| 351.23 | 3.47 | 3.47 |
| 347.29 | 4.64 | 4.64 |
| 379.29 | 4.07 | 4.07 |
| 353.22 | 3.90 | 3.90 |
| 335.23 | 3.76 | 3.76 |
| 352.84 | 4.70 | 4.70 |
| 310.35 | 2.82 | 2.82 |
| 362.83 | 3.56 | 3.56 |
| 418.19 | 5.19 | 5.19 |
| 304.76 | 2.33 | 2.33 |
| 314.77 | 3.47 | 3.47 |
| 314.82 | 3.42 | 3.42 |
| 334.78 | 2.95 | 2.95 |
| 266.30 | 1.90 | 1.90 |
| 414.13 | 4.52 | 4.52 |
| 369.68 | 4.42 | 4.42 |
| 316.81 | 3.85 | 3.85 |
| 312.34 | 3.26 | 3.26 |
| 300.76 | 4.20 | 4.20 |
| 353.22 | 3.90 | 3.90 |
| 316.81 | 3.74 | 3.74 |
| 392.90 | 5.33 | 5.33 |
| 382.87 | 4.70 | 4.70 |
| 330.82 | 3.12 | 3.12 |
| 414.13 | 4.52 | 4.52 |
| 314.82 | 3.30 | 3.30 |
| 409.31 | 4.08 | 4.08 |
| 316.81 | 3.85 | 3.85 |
| 334.78 | 2.95 | 2.95 |
| 369.68 | 4.42 | 4.42 |
| 354.67 | 4.10 | 4.10 |
| 379.29 | 4.07 | 4.07 |
| 310.80 | 2.92 | 2.92 |
| 349.26 | 4.07 | 4.07 |