Basic Information
ID: ALA5135910
Type: Binding
Description: Inhibition of SARS-CoV-2 nsp13 helicase-associated activity using 5'- AGT CTT CTC CTG GTG CTC GAA CAG TGA CCy3-3', 5'- BHQ-2-GTC ACT GTT CGA GCA CCA CCT CTT CTG A-3' DNA as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins in the presence of ATP by fluorescent-based helicase unwind assay
Organism: Severe acute respiratory syndrome coronavirus 2
Activity Charts
Bioactivity
Activity Types for Assay ALA5135910
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 308.39 | 2.95 | 2.95 |
| 558.68 | 6.16 | 6.16 |
| 541.69 | 5.90 | 5.90 |
| 450.58 | 5.57 | 5.57 |
| 436.55 | 5.18 | 5.18 |