Basic Information
ID: ALA5135911
Type: Binding
Description: Inhibition of SARS-CoV-2 nsp13 helicase-associated activity using 5'- AGT CTT CTC CTG GTG CTC GAA CAG TGA CCy3-3', 5'- BHQ-2-GTC ACT GTT CGA GCA CCA CCT CTT CTG A-3' DNA as substrate at highest concentration of compound preincubated for 10 mins followed by substrate addition and measured after 15 mins in the presence of ATP by fluorescent-based helicase unwind assay
Organism: Severe acute respiratory syndrome coronavirus 2
Activity Charts
Bioactivity
Activity Types for Assay ALA5135911
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 541.69 | 5.90 | 5.90 |
| 436.55 | 5.18 | 5.18 |