Assay Report Card

Basic Information

ID: ALA5135921

Type: Binding

Description: Binding affinity to JAK2 JH2 pseudokinase domainV617F mutant in human HEL 92.1.7 assessed as inhibition of STAT5 phosphorylation at 75 uM for 3 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: HEL 92.1.7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
446.473.543.54
460.453.183.18