Basic Information
ID: ALA5135959
Type: Binding
Description: Modulation of CFTR F508 deletion mutant expressed in HBE cells assessed as change in short circuit current incubated for 18 to 24 hrs in presence of forskolin, amiloride and human serum by voltage-clamp based chamber assay
Organism: Homo sapiens
Cell type: HBE
Activity Charts
Bioactivity
Activity Types for Assay ALA5135959
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 442.36 | 4.21 | 4.21 |
| 440.34 | 4.21 | 4.21 |
| 426.32 | 3.83 | 3.83 |
| 442.39 | 4.54 | 4.54 |
| 456.34 | 3.19 | 3.19 |
| 454.37 | 4.46 | 4.46 |