Basic Information
ID: ALA5135968
Type: Binding
Description: Inhibition of recombinant human TET2 catalytic domain assessed as reduction of 5hmC formation at 125 uM using hemi-methylated synthetic oligomer 5'-AATTAGAA[5meC]GCTCCTT-3' as substrate incubated for 30 mins by LC-MS method
Format: BAO_0000357
Organism: Homo sapiens
Target: Methylcytosine dioxygenase TET2(ALA4523344)
Document: ALA5131531
Inhibition of recombinant human TET2 catalytic domain assessed as reduction of 5hmC formation at 125 uM using hemi-methylated synthetic oligomer 5'-AATTAGAA[5meC]GCTCCTT-3' as substrate incubated for 30 mins by LC-MS method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5135968
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 159.61 | ||
| 297.75 | 3.14 | 3.14 |