Assay Report Card

Basic Information

ID: ALA5135977

Type: Binding

Description: Inhibition of recombinant human TET1 catalytic domain assessed as reduction of 5fC formation at 125 uM using hemi-methylated synthetic oligomer 5'-AATTAGAA[5meC]GCTCCTT-3' as substrate measured over 5 to 60 mins by HPLC-ESI-MS/MS method relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
297.753.143.14