Basic Information
ID: ALA5135992
Type: Binding
Description: Antagonist activity at ODN2006 stimulated human TRL9 overexpressed in HEK293 cells assessed as inhibition of NF kappa B/Ap-1 activation preincubated with compound for 30 mins followed by ODN2006 stimulation measured after 22 hrs by SEAP reporter assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5135992
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 377.53 | 4.55 | 4.55 |
| 377.53 | 4.55 | 4.55 |
| 407.56 | 4.56 | 4.56 |
| 378.52 | 3.95 | 3.95 |
| 348.49 | 3.94 | 3.94 |
| 348.49 | 3.94 | 3.94 |
| 378.52 | 3.95 | 3.95 |
| 378.52 | 3.95 | 3.95 |
| 347.51 | 5.44 | 5.44 |
| 378.52 | 3.95 | 3.95 |