Basic Information
ID: ALA5136275
Type: Binding
Description: PROTAC activity at VHL/EGFR L858R/T790M double mutant in gefitinib-resistant human NCI-H1975 cells assessed as EGFR degradation measured after 24 hrs by Immunoblotting analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H1975
Target: VHL/EGFR(ALA4523998)
Document: ALA5131542
PROTAC activity at VHL/EGFR L858R/T790M double mutant in gefitinib-resistant human NCI-H1975 cells assessed as EGFR degradation measured after 24 hrs by Immunoblotting analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5136275
DC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1072.75 |