Basic Information
ID: ALA5136292
Type: Binding
Description: PROTAC activity at CRBN/EGFR in human HCC827 cells assessed as EGFR degradation at 100 nM treated after 4 hrs under serum starvation condition and preincubated with NEDD8 inhibitor MLN4924 for 2 hrs measured after 8 hrs of compound addition by Western blotting analysis
Organism: Homo sapiens
Cell type: HCC827
Activity Charts
Bioactivity
Activity Types for Assay ALA5136292
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 993.49 | 4.07 | 4.07 |