Basic Information
ID: ALA5136296
Type: Binding
Description: PROTAC activity at wild type EGFR/CRBN overexpressed in human OVCAR-8 cells assessed as EGFR degradation upto 10000 nM treated after 8 hrs under serum starvation condition measured after 16 hrs of compound addition by Western blotting analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: OVCAR-8
Target: Protein cereblon/Epidermal growth factor receptor(ALA4523680)
Document: ALA5131542
PROTAC activity at wild type EGFR/CRBN overexpressed in human OVCAR-8 cells assessed as EGFR degradation upto 10000 nM treated after 8 hrs under serum starvation condition measured after 16 hrs of compound addition by Western blotting analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5136296
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 993.49 | 4.07 | 4.07 |