Basic Information
ID: ALA5136300
Type: Binding
Description: PROTAC activity at VHL/wild type EGFR overexpressed in human OVCAR-8 cells assessed as EGFR degradation upto 10000 nM treated after 8 hrs under serum starvation condition and preincubated with GDC-0068 for 2 hrs measured after 16 hrs of compound addition by Western blotting analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: OVCAR-8
Target: VHL/EGFR(ALA4523998)
Document: ALA5131542
PROTAC activity at VHL/wild type EGFR overexpressed in human OVCAR-8 cells assessed as EGFR degradation upto 10000 nM treated after 8 hrs under serum starvation condition and preincubated with GDC-0068 for 2 hrs measured after 16 hrs of compound addition by Western blotting analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5136300
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1056.75 |