Basic Information
ID: ALA5136302
Type: Binding
Description: PROTAC activity at CRBN/wild type EGFR overexpressed in human OVCAR-8 cells assessed as EGFR degradation upto 10000 nM treated after 8 hrs under serum starvation condition and preincubated with 1 to 5 uM pictilisib measured for 2 hrs after 16 hrs of compound addition by Western blotting analysis
Organism: Homo sapiens
Cell type: OVCAR-8
Activity Charts
Bioactivity
Activity Types for Assay ALA5136302
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 887.45 | 6.25 | 6.25 |