Basic Information
ID: ALA5136312
Type: Binding
Description: Binding affinity to VHL/wild type EGFR in human NCI-H1299 cell lysate assessed as ternary complex formation by measuring VHL pulldown at 1 uM pretreated with pictilisib for 2 hrs followed by compound addition measured after 16 hrs by EGFR antibody based co-immunoprecipitation assay
Format: BAO_0000220
Organism: Homo sapiens
Cell type: NCI-H1299
Subcellular Fraction: Lysate
Target: VHL/EGFR(ALA4523998)
Document: ALA5131542
Binding affinity to VHL/wild type EGFR in human NCI-H1299 cell lysate assessed as ternary complex formation by measuring VHL pulldown at 1 uM pretreated with pictilisib for 2 hrs followed by compound addition measured after 16 hrs by EGFR antibody based co-immunoprecipitation assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5136312
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1056.75 |