Basic Information
ID: ALA5136314
Type: Binding
Description: Binding affinity to CRBN/wild type EGFR in human NCI-H1299 cell lysate assessed as ternary complex formation by measuring CRBN pulldown at 1 uM pretreated with pictilisib for 2 hrs followed by compound addition measured after 16 hrs by EGFR antibody based co-immunoprecipitation assay
Organism: Homo sapiens
Cell type: NCI-H1299
Subcellular Fraction: Lysate
Activity Charts
Bioactivity
Activity Types for Assay ALA5136314
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 887.45 | 6.25 | 6.25 |