ID: ALA5136315
Type: Binding
Description: Binding affinity to VHL/wild type EGFR in human OVCAR-8 cell lysate assessed as ternary complex formation by measuring EGFR pulldown at 1 uM pretreated with pictilisib for 2 hrs followed by compound addition measured after 16 hrs by VHL antibody based co-immunoprecipitation assay
Format: BAO_0000220
Organism: Homo sapiens
Cell type: OVCAR-8
Subcellular Fraction: Lysate
Target: VHL/EGFR(ALA4523998)
Document: ALA5131542
Binding affinity to VHL/wild type EGFR in human OVCAR-8 cell lysate assessed as ternary complex formation by measuring EGFR pulldown at 1 uM pretreated with pictilisib for 2 hrs followed by compound addition measured after 16 hrs by VHL antibody based co-immunoprecipitation assay: 1
Bioactivity
Activity Types for Assay ALA5136315
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
1056.75 |