Basic Information
ID: ALA5136318
Type: Binding
Description: Binding affinity to CRBN/wild type EGFR in human NCI-H1299 cell lysate assessed as ternary complex formation by measuring EGFR pulldown at 1 uM pretreated with pictilisib for 2 hrs followed by compound addition measured after 16 hrs by CRBN antibody based co-immunoprecipitation assay
Format: BAO_0000220
Organism: Homo sapiens
Cell type: NCI-H1299
Subcellular Fraction: Lysate
Target: Protein cereblon/Epidermal growth factor receptor(ALA4523680)
Document: ALA5131542
Binding affinity to CRBN/wild type EGFR in human NCI-H1299 cell lysate assessed as ternary complex formation by measuring EGFR pulldown at 1 uM pretreated with pictilisib for 2 hrs followed by compound addition measured after 16 hrs by CRBN antibody based co-immunoprecipitation assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5136318
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 887.45 | 6.25 | 6.25 |