Basic Information
ID: ALA5136324
Type: Binding
Description: PROTAC activity at CRBN/EGFR in human HCC827 cells assessed as EGFR degradation at 100 nM treated after 4 hrs under serum starvation condition and preincubated with gefitinib for 2 hrs measured after 8 hrs of compound addition by Western blotting analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HCC827
Target: Protein cereblon/Epidermal growth factor receptor(ALA4523680)
Document: ALA5131542
PROTAC activity at CRBN/EGFR in human HCC827 cells assessed as EGFR degradation at 100 nM treated after 4 hrs under serum starvation condition and preincubated with gefitinib for 2 hrs measured after 8 hrs of compound addition by Western blotting analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5136324
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 993.49 | 4.07 | 4.07 |