Basic Information
ID: ALA5136395
Type: Functional
Description: Antagonist activity at human wild type A1R expressed in CHO-K1 cells assessed as inhibition of forskolin/ NECA-stimulated cAMP accumulation by measuring NECA-mediated cAMP stimulation at 1 uM incubated with NECA for 30 mins by LANCE cAMP detection assay
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA5136395
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 403.83 | 4.37 | 4.37 |
| 304.39 | 2.36 | 2.36 |
| 308.30 | -1.84 | -1.84 |
| 295.35 | 1.87 | 1.87 |
| 295.35 | 1.87 | 1.87 |
| 281.36 | 3.10 | 3.10 |
| 315.38 | 3.64 | 3.64 |
| 315.38 | 3.64 | 3.64 |
| 281.36 | 3.10 | 3.10 |