Basic Information
ID: ALA5136535
Type: Binding
Description: Inhibition of GCS in human A-375 cells using C6-ceramide and UDP-glucose as substrate preincubated for 30 mins followed by substrate addition measured after 20 hrs by UDP-Glo glucosylceramide synthase based luminometer analysis
Organism: Homo sapiens
Cell type: A-375
Activity Charts
Bioactivity
Activity Types for Assay ALA5136535
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 418.54 | 5.10 | 5.10 |
| 404.51 | 4.71 | 4.71 |
| 442.92 | 4.93 | 4.93 |
| 463.42 | 6.24 | 6.24 |
| 424.88 | 4.67 | 4.67 |
| 380.83 | 4.27 | 4.27 |