Basic Information
ID: ALA5136651
Type: Binding
Description: Time dependent inhibition of recombinant his tagged SARS CoV-2 main protease expressed in Escherichia coli BL21 assessed as ratio of Kinact/Ki using MCA-AVLQSGFR-K(DNP)-K-NH2 as substrate pre-incubated for 5 mins followed by substrate addition measured after 60 mins by FRET based assay
Organism: Severe acute respiratory syndrome coronavirus 2
Activity Charts
Bioactivity
Activity Types for Assay ALA5136651
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.38 | 4.04 | 4.04 |
| 255.30 | 2.89 | 2.89 |
| 334.40 | 4.02 | 4.02 |
| 275.36 | 3.26 | 3.26 |
| 305.18 | 3.13 | 3.13 |
| 282.32 | 3.67 | 3.67 |
| 324.41 | 4.06 | 4.06 |
| 353.49 | 5.96 | 5.96 |
| 327.45 | 5.44 | 5.44 |
| 275.36 | 3.26 | 3.26 |
| 267.31 | 2.96 | 2.96 |
| 298.39 | 4.14 | 4.14 |
| 337.43 | 5.49 | 5.49 |
| 275.36 | 3.26 | 3.26 |
| 275.36 | 3.26 | 3.26 |
| 276.34 | 3.53 | 3.53 |
| 286.38 | 3.93 | 3.93 |
| 301.40 | 3.77 | 3.77 |
| 283.36 | 3.51 | 3.51 |
| 310.40 | 4.71 | 4.71 |
| 416.32 | 6.25 | 6.25 |
| 322.41 | 4.78 | 4.78 |
| 275.36 | 3.26 | 3.26 |
| 289.39 | 3.27 | 3.27 |
| 401.45 | 4.17 | 4.17 |
| 291.36 | 2.96 | 2.96 |
| 261.33 | 2.95 | 2.95 |
| 307.43 | 3.67 | 3.67 |
| 272.35 | 3.62 | 3.62 |
| 269.33 | 3.20 | 3.20 |
| 326.40 | 3.77 | 3.77 |
| 259.29 | 2.79 | 2.79 |
| 377.29 | 4.90 | 4.90 |