Basic Information
ID: ALA5136703
Type: ADME
Description: Metabolic stability in human liver microsomes assessed as apparent clearance at 0.5 uM measured upto 40 mins in presence of NADPH by LCMS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5136703
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 771.36 | 4.15 | 4.15 |
| 504.59 | 4.39 | 4.39 |
| 448.57 | 4.13 | 4.13 |
| 446.56 | 3.60 | 3.60 |
| 476.97 | 4.06 | 4.06 |
| 448.57 | 3.99 | 3.99 |
| 518.62 | 5.00 | 5.00 |
| 428.50 | 3.54 | 3.54 |
| 488.64 | 4.86 | 4.86 |
| 434.54 | 3.74 | 3.74 |
| 830.33 | 4.98 | 4.98 |
| 504.59 | 4.69 | 4.69 |
| 460.58 | 4.08 | 4.08 |
| 490.57 | 4.38 | 4.38 |
| 474.61 | 4.64 | 4.64 |
| 442.52 | 3.41 | 3.41 |
| 505.58 | 3.78 | 3.78 |
| 474.61 | 4.38 | 4.38 |
| 448.57 | 4.13 | 4.13 |
| 495.58 | 3.69 | 3.69 |
| 460.58 | 4.13 | 4.13 |
| 502.66 | 5.42 | 5.42 |
| 518.62 | 4.70 | 4.70 |