Basic Information
ID: ALA5136723
Type: Binding
Description: Positive allosteric modulation of recombinant human GluN1/GluN2B receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamate-induced channel current at -70 mV holding potential by whole cell patch clamp method relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5136723
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 402.66 | 6.50 | 6.50 |
| 456.63 | 7.05 | 7.05 |
| 412.66 | 6.12 | 6.12 |
| 444.74 | 7.67 | 7.67 |
| 416.69 | 6.89 | 6.89 |
| 416.69 | 6.89 | 6.89 |
| 456.63 | 7.05 | 7.05 |
| 446.72 | 6.52 | 6.52 |
| 428.70 | 6.89 | 6.89 |
| 444.74 | 7.67 | 7.67 |
| 430.72 | 7.14 | 7.14 |
| 442.61 | 6.66 | 6.66 |
| 430.72 | 7.14 | 7.14 |
| 456.63 | 7.05 | 7.05 |
| 428.70 | 6.89 | 6.89 |
| 458.65 | 7.13 | 7.13 |