Basic Information
ID: ALA5136851
Type: Binding
Description: Inhibition of recombinant N-terminal GST-tagged human ROCK2 (5 to 554 residues) expressed in baculovirus infected Sf9 cells using S6K as substrate incubated for 30 mins in presence of ATP by ADP Glo kinase assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA5136851
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 247.34 | 2.17 | 2.17 |
| 307.38 | 0.92 | 0.92 |
| 342.40 | 4.14 | 4.14 |
| 405.48 | 3.50 | 3.50 |
| 332.40 | 4.25 | 4.25 |
| 350.39 | 4.39 | 4.39 |
| 390.43 | 3.35 | 3.35 |
| 339.44 | 3.74 | 3.74 |
| 353.47 | 4.13 | 4.13 |
| 355.44 | 2.47 | 2.47 |
| 351.38 | 3.78 | 3.78 |
| 406.89 | 3.86 | 3.86 |
| 333.39 | 3.64 | 3.64 |
| 358.42 | 2.82 | 2.82 |
| 338.45 | 4.24 | 4.24 |
| 382.44 | 2.85 | 2.85 |
| 352.37 | 3.18 | 3.18 |
| 357.43 | 3.88 | 3.88 |
| 352.48 | 4.49 | 4.49 |
| 372.44 | 3.21 | 3.21 |
| 382.44 | 2.85 | 2.85 |
| 352.48 | 4.49 | 4.49 |
| 354.41 | 2.21 | 2.21 |
| 390.43 | 3.35 | 3.35 |
| 353.47 | 4.13 | 4.13 |
| 390.43 | 3.35 | 3.35 |
| 353.47 | 4.13 | 4.13 |
| 372.44 | 3.21 | 3.21 |
| 351.38 | 3.78 | 3.78 |
| 338.45 | 4.24 | 4.24 |
| 390.43 | 3.35 | 3.35 |
| 353.47 | 4.13 | 4.13 |
| 340.43 | 2.68 | 2.68 |