Basic Information
ID: ALA5136914
Type: Binding
Description: Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in SH-SY5Y cells membrane assessed as inhibition constant preincubated for 5 mins followed by overnight incubation with [125I]alpha-bungarotoxin by beta liquid scintilation analysis
Organism: Homo sapiens
Cell type: SH-SY5Y
Subcellular Fraction: Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA5136914
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 451.39 | 5.11 | 5.11 |
| 423.34 | 4.33 | 4.33 |
| 435.35 | 4.47 | 4.47 |
| 529.51 | 6.28 | 6.28 |
| 421.32 | 4.09 | 4.09 |
| 449.38 | 4.87 | 4.87 |
| 435.35 | 4.47 | 4.47 |
| 407.30 | 3.69 | 3.69 |
| 429.30 | 4.22 | 4.22 |
| 461.39 | 4.87 | 4.87 |
| 421.32 | 4.08 | 4.08 |
| 449.38 | 4.86 | 4.86 |
| 447.36 | 4.47 | 4.47 |
| 435.35 | 4.47 | 4.47 |
| 449.38 | 4.86 | 4.86 |
| 466.46 | 6.29 | 6.29 |
| 435.35 | 4.48 | 4.48 |
| 409.31 | 3.94 | 3.94 |
| 437.37 | 4.72 | 4.72 |
| 449.38 | 4.86 | 4.86 |
| 451.35 | 3.71 | 3.71 |
| 477.43 | 5.64 | 5.64 |
| 435.35 | 4.47 | 4.47 |
| 435.35 | 4.47 | 4.47 |
| 421.32 | 4.08 | 4.08 |
| 421.32 | 4.08 | 4.08 |
| 575.53 | 7.47 | 7.47 |
| 545.55 | 7.35 | 7.35 |