Basic Information
ID: ALA5136916
Type: Binding
Description: Displacement of [3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 mins followed by overnight incubation with [3H]-epibatidine by gamma liquid scintilation counting analysis
Organism: Homo sapiens
Cell type: HEK293
Subcellular Fraction: Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA5136916
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 451.39 | 5.11 | 5.11 |
| 435.35 | 4.47 | 4.47 |
| 421.32 | 4.09 | 4.09 |
| 449.38 | 4.87 | 4.87 |
| 407.30 | 3.69 | 3.69 |
| 461.39 | 4.87 | 4.87 |
| 421.32 | 4.08 | 4.08 |
| 447.36 | 4.47 | 4.47 |
| 449.38 | 4.86 | 4.86 |
| 435.35 | 4.48 | 4.48 |
| 449.38 | 4.86 | 4.86 |
| 451.35 | 3.71 | 3.71 |
| 435.35 | 4.47 | 4.47 |
| 435.35 | 4.47 | 4.47 |
| 421.32 | 4.08 | 4.08 |
| 421.32 | 4.08 | 4.08 |