Basic Information
ID: ALA5136919
Type: Binding
Description: Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response treated for 1 sec in presence of acetylcholine at holding potential of -70 mV by two electrode voltage-clamp assay
Organism: Homo sapiens
Cell type: Oocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA5136919
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 451.39 | 5.11 | 5.11 |
| 435.35 | 4.47 | 4.47 |
| 421.32 | 4.09 | 4.09 |
| 449.38 | 4.87 | 4.87 |
| 407.30 | 3.69 | 3.69 |
| 461.39 | 4.87 | 4.87 |
| 421.32 | 4.08 | 4.08 |
| 447.36 | 4.47 | 4.47 |
| 435.35 | 4.47 | 4.47 |
| 435.35 | 4.48 | 4.48 |
| 409.31 | 3.94 | 3.94 |
| 477.43 | 5.64 | 5.64 |
| 421.32 | 4.08 | 4.08 |