Basic Information
ID: ALA5136928
Type: Binding
Description: Inhibition of full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS at 100 uM using tRNA asp as substrate and SAM as co-substrate incubated for 5 mins by tritium incorporation assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5136928
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.42 | -1.44 | -1.44 |
| 340.41 | -0.89 | -0.89 |
| 405.42 | -2.24 | -2.24 |
| 381.39 | -2.06 | -2.06 |
| 381.39 | -2.24 | -2.24 |
| 395.42 | -1.85 | -1.85 |
| 356.39 | -0.18 | -0.18 |
| 337.34 | -2.51 | -2.51 |
| 367.37 | -2.58 | -2.58 |
| 323.36 | -2.03 | -2.03 |
| 381.35 | -3.05 | -3.05 |
| 395.38 | -2.66 | -2.66 |
| 369.40 | -0.37 | -0.37 |
| 372.39 | -0.48 | -0.48 |
| 401.38 | -0.27 | -0.27 |
| 457.49 | -0.67 | -0.67 |
| 437.50 | -0.82 | -0.82 |
| 419.44 | -1.84 | -1.84 |
| 396.36 | -0.68 | -0.68 |
| 449.51 | -0.68 | -0.68 |
| 400.40 | -0.48 | -0.48 |
| 419.44 | -1.84 | -1.84 |
| 419.44 | -1.85 | -1.85 |
| 409.45 | -1.46 | -1.46 |
| 423.47 | -1.07 | -1.07 |
| 433.47 | -1.46 | -1.46 |
| 471.52 | -0.63 | -0.63 |
| 421.46 | -1.46 | -1.46 |
| 379.38 | -2.57 | -2.57 |
| 366.33 | -1.99 | -1.99 |
| 463.54 | -0.29 | -0.29 |
| 433.47 | -1.45 | -1.45 |
| 407.43 | -1.68 | -1.68 |
| 409.45 | -1.46 | -1.46 |
| 423.47 | -1.21 | -1.21 |
| 371.40 | -0.60 | -0.60 |
| 435.49 | -1.07 | -1.07 |
| 352.35 | -1.52 | -1.52 |