Assay Report Card

Basic Information

ID: ALA5136943

Type: Binding

Description: Inhibition of DNMT2-mediated tRNA methylation in human HEK293 cells assessed as reduction in m5C at C38 of tRNA by measuring m5C level at 100 uM incubated for 24 hrs by bisulfite sequencing analysis

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
381.39-2.06-2.06
447.50-1.37-1.37