Basic Information
ID: ALA5137204
Type: Functional
Description: Agonist activity at recombinant human SST4 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production measured after 2.5 to 20 hrs in presence of 3-isobutyl-1-methylxanthine by TR-FRET LANCE assay
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA5137204
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 474.59 | 3.70 | 3.70 |
| 306.37 | 2.71 | 2.71 |
| 492.58 | 3.84 | 3.84 |
| 483.38 | 5.74 | 5.74 |
| 448.93 | 5.09 | 5.09 |
| 471.52 | 5.06 | 5.06 |
| 493.44 | 5.81 | 5.81 |
| 483.38 | 5.74 | 5.74 |
| 516.65 | 6.07 | 6.07 |
| 464.50 | 5.32 | 5.32 |
| 432.48 | 4.58 | 4.58 |
| 426.52 | 4.31 | 4.31 |
| 492.55 | 5.52 | 5.52 |
| 426.52 | 4.31 | 4.31 |
| 394.50 | 4.43 | 4.43 |
| 465.39 | 5.60 | 5.60 |
| 430.94 | 4.95 | 4.95 |
| 421.51 | 4.17 | 4.17 |
| 426.52 | 4.31 | 4.31 |
| 444.51 | 4.44 | 4.44 |
| 442.39 | 5.18 | 5.18 |
| 439.50 | 4.31 | 4.31 |
| 446.51 | 4.77 | 4.77 |
| 414.49 | 4.44 | 4.44 |
| 489.42 | 5.25 | 5.25 |
| 465.39 | 5.60 | 5.60 |
| 493.38 | 5.20 | 5.20 |
| 444.97 | 5.14 | 5.14 |
| 324.36 | 2.85 | 2.85 |
| 494.52 | 5.39 | 5.39 |
| 426.52 | 4.31 | 4.31 |
| 444.51 | 4.44 | 4.44 |
| 482.49 | 5.45 | 5.45 |
| 444.97 | 5.14 | 5.14 |
| 444.51 | 4.44 | 4.44 |
| 414.49 | 4.44 | 4.44 |
| 430.94 | 4.95 | 4.95 |
| 455.52 | 4.40 | 4.40 |
| 456.55 | 4.31 | 4.31 |
| 488.62 | 3.89 | 3.89 |
| 478.52 | 5.51 | 5.51 |
| 435.54 | 4.36 | 4.36 |
| 410.53 | 4.49 | 4.49 |
| 479.42 | 5.80 | 5.80 |
| 440.55 | 4.50 | 4.50 |
| 444.97 | 5.14 | 5.14 |
| 430.94 | 4.95 | 4.95 |
| 494.52 | 5.32 | 5.32 |
| 440.55 | 4.50 | 4.50 |
| 492.58 | 3.84 | 3.84 |
| 396.50 | 4.30 | 4.30 |
| 474.59 | 3.70 | 3.70 |
| 428.52 | 4.63 | 4.63 |
| 444.51 | 4.44 | 4.44 |