Basic Information
ID: ALA5138117
Type: Toxicity
Description: Selectivity index, ratio of CC50 for cytotoxicity against human Huh-5-2 cells carrying HCV subgenomic replicon assessed as decrease in intracellular ATP level to EC50 for antiviral activity against HCV GT-1b Con1 in human Huh-5-2 cells carrying HCV subgenomic replicon assessed as reduction of viral replication
Activity Charts
Bioactivity
Activity Types for Assay ALA5138117
Ratio CC50/EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 784.87 | 5.14 | 5.14 |
| 716.84 | 3.71 | 3.71 |
| 716.84 | 3.71 | 3.71 |
| 780.97 | 3.90 | 3.90 |
| 772.94 | 5.27 | 5.27 |
| 784.87 | 5.14 | 5.14 |
| 784.87 | 5.14 | 5.14 |
| 780.97 | 3.90 | 3.90 |
| 784.87 | 5.14 | 5.14 |
| 780.97 | 3.90 | 3.90 |
| 750.85 | 4.42 | 4.42 |
| 801.00 | 6.05 | 6.05 |
| 744.89 | 4.49 | 4.49 |
| 744.89 | 4.49 | 4.49 |
| 716.84 | 3.71 | 3.71 |
| 716.84 | 3.71 | 3.71 |
| 807.91 | 6.26 | 6.26 |
| 807.91 | 6.26 | 6.26 |
| 744.89 | 4.49 | 4.49 |