Assay Report Card

Basic Information

ID: ALA5138126

Type: Functional

Description: Selectivity index, ratio of EC50 for antiviral activity against HCV GT-1b Con1 in human Huh-5-2 cells carrying HCV subgenomic replicon assessed as drug resistance measured after 15weeks in presence of G418 by NGS analysis to EC50 for antiviral activity against HCV GT-1b Con1 in human Huh-5-2 cells carrying HCV subgenomic replicon assessed as drug resistance measured after 30 passages in presence of G418

Organism: Hepatitis C virus subtype 1b

Strain: Con1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
738.896.226.22
784.875.145.14