Basic Information
ID: ALA5138373
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-primed human THP-1 cells assessed as increase in JNK phosphorylation at 10 uM preincubated for 30 mins followed by nigericin stimulation and measured after 30 mins by western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: NACHT, LRR and PYD domains-containing protein 3(ALA1741208)
Document: ALA5137000
Inhibition of NLRP3 inflammasome activation in LPS-primed human THP-1 cells assessed as increase in JNK phosphorylation at 10 uM preincubated for 30 mins followed by nigericin stimulation and measured after 30 mins by western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5138373
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.30 | 3.05 | 3.05 |