Basic Information
ID: ALA5138382
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in human THP-1 cells assessed as LPS-induced pro-IL-1beta expression level preincubated with LPS for 4 hrs followed by compound treatment for 60 mins by western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: NACHT, LRR and PYD domains-containing protein 3(ALA1741208)
Document: ALA5137000
Inhibition of NLRP3 inflammasome activation in human THP-1 cells assessed as LPS-induced pro-IL-1beta expression level preincubated with LPS for 4 hrs followed by compound treatment for 60 mins by western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5138382
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.30 | 3.05 | 3.05 |