Basic Information
ID: ALA5138391
Type: Binding
Description: Inhibition of AIM2 inflammasome activation in LPS-primed human THP-1 cells assessed as reduction in IL-1beta release in cell supernatant at 0.1 to 10 uM pretreated for 30 mins followed by poly(dA:dT) stimulation and measured after 4 hrs by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: Interferon-inducible protein AIM2(ALA4630802)
Document: ALA5137000
Inhibition of AIM2 inflammasome activation in LPS-primed human THP-1 cells assessed as reduction in IL-1beta release in cell supernatant at 0.1 to 10 uM pretreated for 30 mins followed by poly(dA:dT) stimulation and measured after 4 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5138391
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.30 | 3.05 | 3.05 |