Assay Report Card

Basic Information

ID: ALA5138393

Type: Binding

Description: Inhibition of AIM2 inflammasome activation in LPS-primed human THP-1 cells assessed as activation of caspase-1 at 0.1 to 10 uM pretreated for 30 mins followed by poly(dA:dT) stimulation and measured after 4 hrs by western blot analysis

Organism: Homo sapiens

Cell type: THP-1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
266.303.053.05