Basic Information
ID: ALA5138394
Type: Binding
Description: Inhibition of NLRC4 inflammasome activation in LPS-primed human THP-1 cells infected in salmonella typhimurium assessed as reduction in IL-1beta release in cell supernatant at 0.1 to 10 uM for 30 mins followed by Salmonella infection and measured after 3.5 hrs by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: NLR family CARD domain-containing protein 4(ALA4630857)
Document: ALA5137000
Inhibition of NLRC4 inflammasome activation in LPS-primed human THP-1 cells infected in salmonella typhimurium assessed as reduction in IL-1beta release in cell supernatant at 0.1 to 10 uM for 30 mins followed by Salmonella infection and measured after 3.5 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5138394
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.30 | 3.05 | 3.05 |