Assay Report Card

Basic Information

ID: ALA5138401

Type: Binding

Description: Inhibition of AIM2 inflammasome activation in LPS-primed mouse J774A.1 cells assessed as activation of caspase-1 level at 10 to 100 uM preincubated for 30 mins followed by poly(dA:dT) stimulation and measured after 4 hrs by western blot analysis

Organism: Mus musculus

Cell type: J774.A1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
266.303.053.05