Basic Information
ID: ALA5138409
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-primed human THP-1 cells assessed as supression of NLRP3-ASC interaction at 10 uM preincubated for 30 mins followed by nigericin stimulation and measured after 30 mins by co-immunoprecipitation assay
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA5138409
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.30 | 3.05 | 3.05 |