Basic Information
ID: ALA5138410
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-primed human HEK-293T overexpressing NLRP3 and ASC assessed as supression of NLRP3-ASC interaction at 10 uM incubated for 20 hrs by co-immunoprecipitation assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK-293T
Target: NACHT, LRR and PYD domains-containing protein 3(ALA1741208)
Document: ALA5137000
Inhibition of NLRP3 inflammasome activation in LPS-primed human HEK-293T overexpressing NLRP3 and ASC assessed as supression of NLRP3-ASC interaction at 10 uM incubated for 20 hrs by co-immunoprecipitation assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5138410
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.30 | 3.05 | 3.05 |
| 292.34 | 3.55 | 3.55 |