Assay Report Card

Basic Information

ID: ALA5138410

Type: Binding

Description: Inhibition of NLRP3 inflammasome activation in LPS-primed human HEK-293T overexpressing NLRP3 and ASC assessed as supression of NLRP3-ASC interaction at 10 uM incubated for 20 hrs by co-immunoprecipitation assay

Organism: Homo sapiens

Cell type: HEK-293T

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
266.303.053.05
292.343.553.55